产品
编 号：F755995
分子式：C24H25FN8
分子量：444.51
分子式：C24H25FN8
分子量：444.51
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CAS No: 2785430-85-3
产品详情
生物活性：
ALK5-IN-29 is an selective activin receptor-like kinase (ALK) inhibitor. ALK5-IN-29 can inhibit the activity of ALK5 with an IC50 value of ≤10 nM. ALK5-IN-29 also has inhibitory of tumor growth and can be used for the research of proliferative diseases, such as cancer.
体外研究：
ALK5-IN-29 (EX-06) has kinase inhibition of ALK5 with an IC50 value of ≤10 nM.ALK5-IN-29 has kinase selectivity of ALK2/ALK5 with an IC50 value of ≤10 nM.ALK5-IN-29 shows TGFB-RI inhibition (RD-SMAD receptor activity) with an IC50 value of ≤100 nM.
ALK5-IN-29 is an selective activin receptor-like kinase (ALK) inhibitor. ALK5-IN-29 can inhibit the activity of ALK5 with an IC50 value of ≤10 nM. ALK5-IN-29 also has inhibitory of tumor growth and can be used for the research of proliferative diseases, such as cancer.
体外研究：
ALK5-IN-29 (EX-06) has kinase inhibition of ALK5 with an IC50 value of ≤10 nM.ALK5-IN-29 has kinase selectivity of ALK2/ALK5 with an IC50 value of ≤10 nM.ALK5-IN-29 shows TGFB-RI inhibition (RD-SMAD receptor activity) with an IC50 value of ≤100 nM.
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