产品
编 号：F755945
分子式：C60H76ClFN10O8S
分子量：1151.82
分子式：C60H76ClFN10O8S
分子量：1151.82
产品类型
规格
价格
是否有货
结构图
CAS No: 2772612-96-9
产品详情
生物活性：
MS9449 is a potent PROTAC EGFR degrader with Kds of 17 nM and 10 nM for EGFR WT and EGFR L858R, respectively. MS9449 effectively induces degradation of mutant EGFRs through both the ubiquitin/proteasome system (UPS) and autophagy/lysosome pathways. MS9449 potently inhibits the proliferation of NSCLC cells. MS9449 can be used for researching anticancer.
MS9449 is a potent PROTAC EGFR degrader with Kds of 17 nM and 10 nM for EGFR WT and EGFR L858R, respectively. MS9449 effectively induces degradation of mutant EGFRs through both the ubiquitin/proteasome system (UPS) and autophagy/lysosome pathways. MS9449 potently inhibits the proliferation of NSCLC cells. MS9449 can be used for researching anticancer.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备