产品
编 号：F755848
分子式：C27H22ClN7O3S
分子量：560.03
分子式：C27H22ClN7O3S
分子量：560.03
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CAS No: 2768005-77-0
产品详情
生物活性：
PI3K-IN-29 is a potent PI3K inhibitor. PI3K-IN-29 displays good inhibition potencies against U87MG, HeLa and HL60 cells with IC50 values of 0.264, 2.04 and 1.14 μM, respectively. PI3K-IN-29 inhibits PI3K/Akt pathway by inhibiting phosphorylation of Akt that is catalyzed by PI3K.
体外研究：
PI3K-IN-29 (compound 25) (72 h) displays good inhibition potencies against U87MG, HeLa and HL60 cells with IC50 values of 0.264, 2.04 and 1.14 μM, respectively.PI3K-IN-29 (U87MG cells; 1, 5 μM; 1 h) inhibits PI3K/Akt pathway by inhibiting phosphorylation of Akt that is catalyzed by PI3K.
PI3K-IN-29 is a potent PI3K inhibitor. PI3K-IN-29 displays good inhibition potencies against U87MG, HeLa and HL60 cells with IC50 values of 0.264, 2.04 and 1.14 μM, respectively. PI3K-IN-29 inhibits PI3K/Akt pathway by inhibiting phosphorylation of Akt that is catalyzed by PI3K.
体外研究：
PI3K-IN-29 (compound 25) (72 h) displays good inhibition potencies against U87MG, HeLa and HL60 cells with IC50 values of 0.264, 2.04 and 1.14 μM, respectively.PI3K-IN-29 (U87MG cells; 1, 5 μM; 1 h) inhibits PI3K/Akt pathway by inhibiting phosphorylation of Akt that is catalyzed by PI3K.
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