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编 号:F755842
分子式:C16H12FNO2
分子量:269.27
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生物活性:
Tubulin inhibitor 15 is a potent tubulin inhibitor. Tubulin inhibitor 15 shows antiproliferative activity. Tubulin inhibitor 15 shows cytotoxicity in HepG2 cells.

体外研究:
Tubulin inhibitor 15 (compound 6) (0-25 μM, 24 h followed by a 72 h compound-free incubation period) shows antiproliferative activity with IC50s of 1.60, 0.22, 1.40, 0.68, 0.47, 0.21, >25 μM for MCF7, MDA-MB-231, HepG2, SNU423, A549, HCT116, THLE-3 cells.
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