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编 号:F755821
分子式:C14H22N4O5S
分子量:358.41
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生物活性:
Iroxanadine ((-)-BRX 005) sulfate is a potent activator of p38 kinase, and an enhancer of stress-responsive heat shock protein (Hsp) expression. Iroxanadine sulfate also is a vasculoprotector against atherosclerosis. Iroxanadine sulfate may improve survival of vascular endothelial cells (ECs) following ischemia/reperfusion stress.

体外研究:
缺氧前或复氧开始时向培养基中加入 Iroxanadine sulfate (0.1-1 μM) 可显著减少 caspase 依赖性细胞凋亡。
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