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编 号:F755809
分子式:C19H18F3N3O
分子量:361.36
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CAS No: 2766575-48-6
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SWTX-143 is a novel covalent YAP/TAZ-TEAD inhibitor that binds to the palmitoylation pocket of all four TEAD isoforms. SWTX-143 causes irreversible and specific inhibition of the transcriptional activity of YAP/TAZ-TEAD and shows antitumor activity.