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编 号:F755794
分子式:C18H20F3N3O2
分子量:367.37
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生物活性:
NOS-IN-2 (Compound 4i) is a potent, selective, imidamide derived NOS inhibitor with an IC50 against iNOS of 20 μM, without inhibiting eNOS. NOS-IN-2 has little toxicity and can be used for studying inflammatory disorders.

体内研究:
NOS-IN-2 (Compound 4i) is predicted to show oral bioavailability.

体外研究:
NOS-IN-2 (Compound 4i) shows high iNOS selectivity without eNOS inhibition activity .NOS-IN-2 (0-100 μM, 30 min) has little toxicity.
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