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编 号:F755791
分子式:C16H8N2O3
分子量:276.25
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生物活性:
Antitumor agent-43 (Compound 4B) is a potent antitumor agent, with an IC50of 0.5 μM for (T-24 cell). Antitumor agent-43 (Compound 4B) induces cell cycle arrest at G2/M phase.

体内研究:
Antitumor agent-43 effectively inhibits tumor growth (49.5%) in a mouse xenograft model bearing T-24. .

体外研究:
Antitumor agent-43 towards T-24, MGC80-3, SK-OV-3, HepG2 cells with IC50of 0.5, 1.1, 8.9 and 1.3μM, respectively.
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