产品
编 号：F755773
分子式：C27H27Cl2N3O
分子量：480.43
分子式：C27H27Cl2N3O
分子量：480.43
产品类型
规格
价格
是否有货
结构图
CAS No: 2765539-59-9
产品详情
生物活性：
LSN3160440 is an allosteric modulator of GLP-1R, which acts as a protein–protein interaction (PPI) stabilizer or molecular glue to assist in the adhesion of inactive GLP-1 (9-36) NH2 on GLP-1R.
体外研究：
LSN3160440 binds between the TM1 and TM2 interfaces of GLP-1R, and the benzimidazole group of LSN3160440 interacts with GLP-1R in a variety of ways, such as van der Waals contacts with Leu142, π?π stacking with Tyr145, and frequent water bridging with Lys202.
LSN3160440 is an allosteric modulator of GLP-1R, which acts as a protein–protein interaction (PPI) stabilizer or molecular glue to assist in the adhesion of inactive GLP-1 (9-36) NH2 on GLP-1R.
体外研究：
LSN3160440 binds between the TM1 and TM2 interfaces of GLP-1R, and the benzimidazole group of LSN3160440 interacts with GLP-1R in a variety of ways, such as van der Waals contacts with Leu142, π?π stacking with Tyr145, and frequent water bridging with Lys202.
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