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编 号:F755632
分子式:C15H22Cl2N8O
分子量:401.29
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生物活性:
DNA crosslinker 2 (dihydrochloride) is a potent DNA minor groove binder with DNA binding affinity (ΔTm) of 1.2 °C. DNA crosslinker 2 (dihydrochloride) has certain inhibitory activity against cancer cells NCI-H460, A2780 and MCF-7. DNA crosslinker 2 (dihydrochloride) can be used for researching anticancer.

体外研究:
DNA crosslinker 2 (dihydrochloride) (compound 3) (100 μM; 48 h or 96 h) exhibits inhibitory activity against NCI-H460, A2780 and MCF-7.
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