产品
编 号：F755619
分子式：C20H19N3O4
分子量：365.38
分子式：C20H19N3O4
分子量：365.38
产品类型
规格
价格
是否有货
结构图
CAS No: 2761542-55-4
产品详情
生物活性：
AChE/BChE-IN-9 (Compound 7a) is a potent, orally active AChE and BChE inhibitor with IC50 values of 5.74 μM and 14.05 μM against hAChE and eqBChE, respectively. AChE/BChE-IN-9 is also an efficacious antioxidant with an IC50 of 57.35 μM. AChE/BChE-IN-9 is able to chelate iron and modulates aggregation of amyloid β1-42. AChE-IN-16 can cross the BBB.
体内研究：
AChE/BChE-IN-9 (Compound 7a) (0-25 mg/kg) improves spatial memory in cognitive deficit mice.
AChE/BChE-IN-9 (Compound 7a) is a potent, orally active AChE and BChE inhibitor with IC50 values of 5.74 μM and 14.05 μM against hAChE and eqBChE, respectively. AChE/BChE-IN-9 is also an efficacious antioxidant with an IC50 of 57.35 μM. AChE/BChE-IN-9 is able to chelate iron and modulates aggregation of amyloid β1-42. AChE-IN-16 can cross the BBB.
体内研究：
AChE/BChE-IN-9 (Compound 7a) (0-25 mg/kg) improves spatial memory in cognitive deficit mice.
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