产品
编 号：F755568
分子式：C45H49ClFN7O8S
分子量：902.43
分子式：C45H49ClFN7O8S
分子量：902.43
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CAS No: 2760536-88-5
产品详情
生物活性：
Bcl-2-IN-11 (compound 6) is a potent and selective Bcl-2 activity inhibitor, with an IC50 of 0.9 nM. Bcl-2-IN-11 shows weak inhibition of Bcl-xl (IC50 > 1000 nM). Bcl-2-IN-11 can be used for the research of a variety of cancers caused by abnormal overexpression of Bcl-2 family proteins: especially malignant hematologic diseases of acute lymphoid leukemia, etc. Bcl-2-IN-11 can also avoid toxic side effects caused by Bcl-xl inhibition, such as thrombocytopenia.
体外研究：
Bcl-2-IN-11 (compound 6) 可抑制 RS4;11 急性淋巴细胞增殖，IC50 为 2.37 nM。
Bcl-2-IN-11 (compound 6) is a potent and selective Bcl-2 activity inhibitor, with an IC50 of 0.9 nM. Bcl-2-IN-11 shows weak inhibition of Bcl-xl (IC50 > 1000 nM). Bcl-2-IN-11 can be used for the research of a variety of cancers caused by abnormal overexpression of Bcl-2 family proteins: especially malignant hematologic diseases of acute lymphoid leukemia, etc. Bcl-2-IN-11 can also avoid toxic side effects caused by Bcl-xl inhibition, such as thrombocytopenia.
体外研究：
Bcl-2-IN-11 (compound 6) 可抑制 RS4;11 急性淋巴细胞增殖，IC50 为 2.37 nM。
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