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编 号:F755336
分子式:C28H26N4O3
分子量:466.53
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生物活性:
CCG-271423 is a potent and selective GRK5 inhibitor with IC50 values of 0.0021 μM and 44 μM for GRK5 and GRK2, respectively. CCG-271423 inhibits cardiomyocyte contractility and decreases in Ca2+ transience. CCG-271423 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

体外研究:
CCG-271423 (1 μM) does not alter cardiomyocyte contractility and decreases in Ca2+ transience.
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