产品
编 号:F755252
分子式:C25H30ClFN2O
分子量:428.97
产品类型
结构图
CAS No: 2748337-90-6
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产品详情
生物活性:
BM635 hydrochloride is a?MmpL3?inhibitor with outstanding anti-mycobacterial activity. BM635 hydrochloride has an MIC50 of 0.08 μM against M.tuberculosis H37Rv. BM635 hydrochloride doubles the in vivo exposure with respect to the free base BM635.
体内研究:
BM635 hydrochloride (oral administration; 50 mg/Kg) results in gradual elevations in blood up to a Cmax of 579.1 ng/ml with Tmax of 3 hour. It doubles the in vivo exposure with respect to the free base BM635 in C57BL/6J mice.