产品
编 号:F755162
分子式:C56H79ClN12O6S2
分子量:1115.89
产品类型
结构图
CAS No: 2740582-16-3
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产品详情
生物活性:
SHP2 protein degrader-2 (SHP2-D26) is a SHP2 protein PROTAC degrader. SHP2 protein degrader-2 reduces expression level of SHP2 in various cancer cells.
体外研究:
SHP2 protein degrader-2 (SHP2-D26) achieves excellent degradation of SHP2 with the DC50 (the concentration where 50% of the protein has been degraded) values of 2.6 nM and 6.0 nM for MV4;11 and KYSE520 cells, respectively.