产品
编 号：F755102
分子式：C17H11ClF7N3O
分子量：441.73
分子式：C17H11ClF7N3O
分子量：441.73
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
结构图
CAS No: 2734922-78-0
产品详情
生物活性：
HIF-2α-IN-8 is a potent and orally active HIF2α inhibitor with IC50 values of 9, 37, 246 nM for HIF2α SPA, HIF2α iScript, HIF2α HRE RGA, respectively. HIF-2α-IN-8 shows antitumor activity.
体内研究：
HIF-2α-IN-8 (Example 31) (30 mg/kg; p.o.; daily for 21 days) 在小鼠体内显示出抗肿瘤活性。Animal Model:6-9 weeks, female nude Crl:NU(NCr)-Foxn1nu-Homozygous mice (786-O mouse model)
Dosage:30 mg/kg
Administration:P.o.; started 34 days post tumor inoculation; daily for 21 days
Result:Inhibited the tumor growth.
HIF-2α-IN-8 is a potent and orally active HIF2α inhibitor with IC50 values of 9, 37, 246 nM for HIF2α SPA, HIF2α iScript, HIF2α HRE RGA, respectively. HIF-2α-IN-8 shows antitumor activity.
体内研究：
HIF-2α-IN-8 (Example 31) (30 mg/kg; p.o.; daily for 21 days) 在小鼠体内显示出抗肿瘤活性。Animal Model:6-9 weeks, female nude Crl:NU(NCr)-Foxn1nu-Homozygous mice (786-O mouse model)
Dosage:30 mg/kg
Administration:P.o.; started 34 days post tumor inoculation; daily for 21 days
Result:Inhibited the tumor growth.
产品资料
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