产品
编 号：F754987
分子式：C24H23Br2N3O6
分子量：609.26
分子式：C24H23Br2N3O6
分子量：609.26
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CAS No: 2725075-01-2
产品详情
生物活性：
Chitin synthase inhibitor 10 is a chitin synthase inhibitor. Chitin synthase inhibitor 10 shows excellent chitin synthase inhibitory activity with an IC50 value of 0.11 mM. Chitin synthase inhibitor 10 also is an antifungal agent and has significantly antifungal activity against drug-resistant fungal variants, such as C. albicans and C. neoformans. Chitin synthase inhibitor 10 can be used for the research of invasive fungal infections (IFIs).
体外研究：
Chitin synthase inhibitor 10 (compound 9o) (300 ug/mL) has good inhibitory activity against chitin synthase with with an IC50 value of 0.11 mM.Chitin synthase inhibitor 10 has antifungal activity for C. albicans, A. flavus, A. fumigatus and C. neoformans with MIC values of 64 μg/mL, 256 μg/mL, 128 μg/mL and 64 μg/mL, respectively.Chitin synthase inhibitor 10 is related to the disruption of cell wall architecture.
Chitin synthase inhibitor 10 is a chitin synthase inhibitor. Chitin synthase inhibitor 10 shows excellent chitin synthase inhibitory activity with an IC50 value of 0.11 mM. Chitin synthase inhibitor 10 also is an antifungal agent and has significantly antifungal activity against drug-resistant fungal variants, such as C. albicans and C. neoformans. Chitin synthase inhibitor 10 can be used for the research of invasive fungal infections (IFIs).
体外研究：
Chitin synthase inhibitor 10 (compound 9o) (300 ug/mL) has good inhibitory activity against chitin synthase with with an IC50 value of 0.11 mM.Chitin synthase inhibitor 10 has antifungal activity for C. albicans, A. flavus, A. fumigatus and C. neoformans with MIC values of 64 μg/mL, 256 μg/mL, 128 μg/mL and 64 μg/mL, respectively.Chitin synthase inhibitor 10 is related to the disruption of cell wall architecture.
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