产品
编 号:F754970
分子式:C25H40O5
分子量:420.58
产品类型
结构图
CAS No: 27240-87-5
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产品详情
生物活性:
BAA473 is a bile acid analog and is a potent activator of the pyrin inflammasome that induces the secretion of interleukin 18 (IL-18) through activation of the inflammasome in both myeloid and intestinal epithelial cells.
体外研究:
BAA473 (0-33 μM; 24 hours; THP-1-Cas9 cells) treatment induces cell death in LPS-primed THP-1-Cas9 cells.