产品
编 号：F754884
分子式：C11H7D5N2O2
分子量：209.26
分子式：C11H7D5N2O2
分子量：209.26
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CAS No: 2714409-09-1
产品详情
生物活性：
Ethotoin-d5 is the deuterium labeled Ethotoin. Ethotoin (Peganone) is an orally active anticonvulsant agent used in epilepsy research, Ethotoin is a hydantoin, similar to phenytoin.
体内研究：
After dosing Ethotoin on gestational day 18, offspring exhibits mild mortality and weight loss.Animal Model:Pregnant Sprague-Dawley CD rats
Dosage:600 mg/kg
Administration:Oral gavage, 600 mg/kg, once
Result:Preweaning mortality for Ethotoin was 2.0%, Ethotoin -exposed animals weighed approximately 6.6% less than controls.
体外研究：
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Ethotoin-d5 is the deuterium labeled Ethotoin. Ethotoin (Peganone) is an orally active anticonvulsant agent used in epilepsy research, Ethotoin is a hydantoin, similar to phenytoin.
体内研究：
After dosing Ethotoin on gestational day 18, offspring exhibits mild mortality and weight loss.Animal Model:Pregnant Sprague-Dawley CD rats
Dosage:600 mg/kg
Administration:Oral gavage, 600 mg/kg, once
Result:Preweaning mortality for Ethotoin was 2.0%, Ethotoin -exposed animals weighed approximately 6.6% less than controls.
体外研究：
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
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