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编 号：F754768
分子式：C29H26F2N4O7S
分子量：612.6
分子式：C29H26F2N4O7S
分子量：612.6
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CAS No: 2703046-92-6
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生物活性：
Influenza virus-IN-7 (Example 16) is an orally active cap-dependent endonuclease inhibitor that can be used for the research of influenza viral infectious diseases.
体内研究：
Influenza virus-IN-7 (Example 16; 5 mg/kg; i.g.; twice daily for 5 days) 可提高 WSN/33 (H1N1) 感染小鼠模型的存活率。Animal Model:WSN/33 (H1N1) infection mouse model
Dosage:5 mg/kg
Administration:Intragastric administration, twice daily for 5 days
Result:Significantly improved the survival rate.
体外研究：
Influenza virus-IN-7 (Example 16) 在 MDCK 细胞中显示出对流感 A/Weiss/43(H1N1) 病毒的抗病毒活性，EC50 为 1000 nM)。
Influenza virus-IN-7 (Example 16) is an orally active cap-dependent endonuclease inhibitor that can be used for the research of influenza viral infectious diseases.
体内研究：
Influenza virus-IN-7 (Example 16; 5 mg/kg; i.g.; twice daily for 5 days) 可提高 WSN/33 (H1N1) 感染小鼠模型的存活率。Animal Model:WSN/33 (H1N1) infection mouse model
Dosage:5 mg/kg
Administration:Intragastric administration, twice daily for 5 days
Result:Significantly improved the survival rate.
体外研究：
Influenza virus-IN-7 (Example 16) 在 MDCK 细胞中显示出对流感 A/Weiss/43(H1N1) 病毒的抗病毒活性，EC50 为 1000 nM)。
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