产品
编 号：F754757
分子式：C17H22N4O
分子量：298.38
分子式：C17H22N4O
分子量：298.38
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
询价
询价
5mg
询价
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10mg
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询价
结构图
CAS No: 2702280-86-0
产品详情
生物活性：
MS117 is a first-in-class and cell-active irreversible protein arginine methyltransferase 6 (PRMT6) covalent inhibitor, with an IC50 of 18 nM.
体外研究：
MS117 (Compound 4) inhibits the PRMT6 methyltransferase activity in a time-dependent manner.MS117 (Compound 4) shows moderate selectivity (6-fold) for PRMT6 over PRMT1 (IC50 = 0.1 ± 0.025 μM) and PRMT8 (IC50 = 0.11 ± 0.01 μM) .
MS117 is a first-in-class and cell-active irreversible protein arginine methyltransferase 6 (PRMT6) covalent inhibitor, with an IC50 of 18 nM.
体外研究：
MS117 (Compound 4) inhibits the PRMT6 methyltransferase activity in a time-dependent manner.MS117 (Compound 4) shows moderate selectivity (6-fold) for PRMT6 over PRMT1 (IC50 = 0.1 ± 0.025 μM) and PRMT8 (IC50 = 0.11 ± 0.01 μM) .
产品资料
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