产品
编 号:F754686
分子式:C72H79FN10O17
分子量:1375.45
产品类型
结构图
CAS No: 2694856-51-2
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产品详情
生物活性:
DBCO-PEG4-GGFG-Dxd is a agent-linker conjugate for ADC with potent antitumor activity by using Dxd (a DNA topoisomerase I inhibitor), linked via the cleavable ADC linker DBCO-PEG4-GGFG. DBCO-PEG4-GGFG-Dxd is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
体外研究:
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linke.