产品
编 号:F754643
分子式:C26H25FN4O4
分子量:476.5
产品类型
结构图
CAS No: 2688745-47-1
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产品详情
生物活性:
Y08284 is a potent, selective, oral active CBP bromodomain inhibitor with an IC50 of 4.21 nM. Y08284 suppresses the proliferation of prostate cancer cell lines LNCaP, C4-2B, and 22Rv1. Antitumor activity.
体内研究:
Y08284 demonstrates favorable cell permeability and good pharmacokinetic properties, with oral bioavailability of 25.9%.