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编 号:F754643
分子式:C26H25FN4O4
分子量:476.5
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生物活性:
Y08284 is a potent, selective, oral active CBP bromodomain inhibitor with an IC50 of 4.21 nM. Y08284 suppresses the proliferation of prostate cancer cell lines LNCaP, C4-2B, and 22Rv1. Antitumor activity.

体内研究:
Y08284 demonstrates favorable cell permeability and good pharmacokinetic properties, with oral bioavailability of 25.9%.
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