产品
编 号:F754601
分子式:C49H59ClN8O8S2
分子量:987.62
产品类型
结构图
CAS No: 2683008-37-7
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产品详情
生物活性:
OARV-771 is a VHL-based BET degrader (PROTAC) with improved cell permeability. OARV-771 shows DC50s of 6, 1, and 4 nM for Brd4, Brd2 and Brd3, respectively.
体外研究:
OARV-771 shows antiproliferative effect with an EC50 value of 4 nM in MV4;11.