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编 号:F754595
分子式:C36H46BrN8O2P
分子量:733.68
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生物活性:
EGFR-IN-29 is a potent EGFR inhibitor, example J-022, extracted from Patent WO2021160087.

体外研究:
EGFR-IN-29 inhibits Ba/F3 cells with stable overexpression of △19del/T790M/C797S mutant genes, cells overexpressing EGFR WT and A431 carrying EGFR WT with IC50 values of 6.8 nM, 151 nM and 1128 nM, respectively.
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