产品
编 号：F754416
分子式：C39H47N13O6S
分子量：825.94
分子式：C39H47N13O6S
分子量：825.94
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规格
价格
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结构图
CAS No: 2653337-73-4
产品详情
生物活性：
STING agonist-9 (Compound 45) is a potent STING agonist with an EC50 of 1.2 nM and 32.82 μM against h-STING and m-STING, respectively. STING agonist-9 shows antitumor activity.
体内研究：
STING agonist-9 (Compound 45) significantly inhibits the tumor growth in allograft 4T1 and CT26 tumor models by systemic administration, and induces tumor regression in CT26 tumor model without inducing weight loss.
体外研究：
STING agonist-9 (Compound 45) directly binds to various h-STING isoforms and m-STING.STING agonist-9 potently activates both ISG and NF-κB signaling pathways.
STING agonist-9 (Compound 45) is a potent STING agonist with an EC50 of 1.2 nM and 32.82 μM against h-STING and m-STING, respectively. STING agonist-9 shows antitumor activity.
体内研究：
STING agonist-9 (Compound 45) significantly inhibits the tumor growth in allograft 4T1 and CT26 tumor models by systemic administration, and induces tumor regression in CT26 tumor model without inducing weight loss.
体外研究：
STING agonist-9 (Compound 45) directly binds to various h-STING isoforms and m-STING.STING agonist-9 potently activates both ISG and NF-κB signaling pathways.
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