产品
编 号：F754388
分子式：C20H21N3O3S
分子量：383.46
分子式：C20H21N3O3S
分子量：383.46
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 2649776-79-2
产品详情
生物活性：
MPH-220 is a selective and orally active inhibitor of skeletal muscle myosin-2. MPH-220 enables muscle relaxation. MPH-220 is anti-spastic agent that can be used in the research of spasticity and muscle stiffness.
体内研究：
MPH-220 (25-30 mg/kg，腹腔注射或口服灌胃) 可降低麻醉大鼠的骨骼肌力量，而不会影响心血管。MPH-220 (15 mg/kg，口服) 改善脑损伤大鼠的步态功能。Animal Model:Anesthetized rats
Dosage:25-30 mg/kg
Administration:Intraperitoneal injection (i.p.) or oral gavage
Result:Reduced skeletal muscle force.Observed MPH-220 distribution in rat tissues in a time-dependent manner and a dose-dependent, few-fold accumulation in skeletal muscle.
体外研究：
MPH-220 (0-50 μM) 抑制人肌肉肌球蛋白样品中肌动蛋白激活的 ATP 酶活性。
MPH-220 is a selective and orally active inhibitor of skeletal muscle myosin-2. MPH-220 enables muscle relaxation. MPH-220 is anti-spastic agent that can be used in the research of spasticity and muscle stiffness.
体内研究：
MPH-220 (25-30 mg/kg，腹腔注射或口服灌胃) 可降低麻醉大鼠的骨骼肌力量，而不会影响心血管。MPH-220 (15 mg/kg，口服) 改善脑损伤大鼠的步态功能。Animal Model:Anesthetized rats
Dosage:25-30 mg/kg
Administration:Intraperitoneal injection (i.p.) or oral gavage
Result:Reduced skeletal muscle force.Observed MPH-220 distribution in rat tissues in a time-dependent manner and a dose-dependent, few-fold accumulation in skeletal muscle.
体外研究：
MPH-220 (0-50 μM) 抑制人肌肉肌球蛋白样品中肌动蛋白激活的 ATP 酶活性。
产品资料
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