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编 号：F754325
分子式：C32H39IN6O3
分子量：682.59
分子式：C32H39IN6O3
分子量：682.59
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CAS No: 2648221-12-7
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生物活性：
KRAS G12D inhibitor 16 is a KRAS G12D inhibitor. KRAS G12D inhibitor 16 has inhibitory activity against KRAS G12D and KRAS G12D mutation with IC50 value of 0.7 nM and 0.35 μM, respectively. KRAS G12D inhibitor 16 can be used for the research of many malignant tumor, such as pancreatic ductal adenocarcinomas (PDAC), colon and rectal carcinomas (CRC), non-small cell lung carcinomas (NSCLC).
体外研究：
KRAS G12D inhibitor 16 has inhibitory activity for G12 with an IC50 value of 0.7 nM.KRAS G12D inhibitor 16 shows growth inhibition activity KRAS-G12D mutant cell line (A-427) with an IC50 value of 0.35 μM.
KRAS G12D inhibitor 16 is a KRAS G12D inhibitor. KRAS G12D inhibitor 16 has inhibitory activity against KRAS G12D and KRAS G12D mutation with IC50 value of 0.7 nM and 0.35 μM, respectively. KRAS G12D inhibitor 16 can be used for the research of many malignant tumor, such as pancreatic ductal adenocarcinomas (PDAC), colon and rectal carcinomas (CRC), non-small cell lung carcinomas (NSCLC).
体外研究：
KRAS G12D inhibitor 16 has inhibitory activity for G12 with an IC50 value of 0.7 nM.KRAS G12D inhibitor 16 shows growth inhibition activity KRAS-G12D mutant cell line (A-427) with an IC50 value of 0.35 μM.
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