产品
编 号:F754226
分子式:C19H23ClN2O2
分子量:346.85
产品类型
结构图
CAS No: 2640366-38-5
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产品详情
生物活性:
FTO-IN-8 (FTO-43) is a N6-methyladenosine demethylase (FTO) (fat mass- and obesity-associated protein) inhibitor with the IC50 value of 5.5 μM. FTO-IN-8 has anti-cancer cell proliferative activity.
体外研究:
FTO-IN-8 (FTO-43) (0-50 μM, 24-72 h) inhibits the proliferation of cancer cells with no cytotoxicity to normal colonic cells.FTO-IN-8 (FTO-43) can increase m6A and m6Am levels and inhibits Wnt/PI3K-Akt signaling in gastric cancer AGS cells.