产品
编 号:F754123
分子式:C22H21ClF2N2O4
分子量:450.86
产品类型
结构图
CAS No: 2629177-12-2
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产品详情
生物活性:
ZK824190 hydrochloride is an orally available and selective urokinase plasminogen activator (uPA) inhibitor as a potential treatment for multiple sclerosis. IC50s of 237, 1600 and 1850 nM for uPA, tPA, and Plasmin, respectively.
体内研究:
ZK824190 (2?mg/kg; PO; Rats with EAE model) exhibits a relatively high oral availability and a moderate half time (T1/2=2.8 h).