产品
编 号：F753953
分子式：C18H14FNO3
分子量：311.31
分子式：C18H14FNO3
分子量：311.31
产品类型
规格
价格
是否有货
结构图
CAS No: 2588211-50-9
产品详情
生物活性：
Topoisomerase I inhibitor 3 (Compound ZML-14) is a topoisomerase I inhibitor and can interact with topoisomerase I-DNA complex. Topoisomerase I inhibitor 3 induces HepG2 cell apoptosis and arrests cell cycle at G2/M phase.
体外研究：
Topoisomerase I inhibitor 3 (Compound ZML-14) shows cytotoxicity with IC50 values of 1.94 ± 0.09, 10.32 ± 0.39, 13.1 ± 0.96, 40.69 ± 5.36, 28.11 ± 2.50, >100 and 37.42 ± 2.05 μM against HepG2, A2780, HeLa, HCT116, SW1990, MCF7 and L-02 cells, respectively.
Topoisomerase I inhibitor 3 (Compound ZML-14) is a topoisomerase I inhibitor and can interact with topoisomerase I-DNA complex. Topoisomerase I inhibitor 3 induces HepG2 cell apoptosis and arrests cell cycle at G2/M phase.
体外研究：
Topoisomerase I inhibitor 3 (Compound ZML-14) shows cytotoxicity with IC50 values of 1.94 ± 0.09, 10.32 ± 0.39, 13.1 ± 0.96, 40.69 ± 5.36, 28.11 ± 2.50, >100 and 37.42 ± 2.05 μM against HepG2, A2780, HeLa, HCT116, SW1990, MCF7 and L-02 cells, respectively.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备