产品
编 号:F753841
分子式:C45H51F3N8O7
分子量:872.93
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1mg
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生物活性:
KTX-582 is a potent IRAK4 degrader with DC50 values of 4 nM and 5 nM for IRAK4 and Ikaros, respectively. KTX-582 can induce apoptosis in MYD88MT DLBCL, and is efficient to induce in vivo tumor regressions in lymphoma model.

体外研究:
KTX-582 (compound I-41) degrades IRAK4 in whole blood monocyte and lymphocyte with IC50s of KTX-582 相关抗体:
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