产品
编 号:F753836
分子式:C26H26N6O2
分子量:454.52
产品类型
结构图
CAS No: 2573048-10-7
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产品详情
生物活性:
BTK-IN-22 is a BTK inhibitor (IC50: 0.9 nM). BTK-IN-22 also inhibits BLX and BMX with IC50s of 1.4 and 1.2 nM respectively. BTK-IN-22 shows improved kinase selectivity compared to Ibrutinib (HY-10997)
体外研究:
BTK-IN-23 (Compound 2) 抑制 Jeko-1 细胞中 BTK 自磷酸化,IC50 值为 109 nM.