产品
编 号:F753791
分子式:C26H37N7O2
分子量:479.62
产品类型
结构图
CAS No: 2567953-47-1
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产品详情
生物活性:
TLR7/8 agonist 7 (compound 10) is a TLR7/8 agonist. TLR7/8 agonist 7 activates a variety of immune cells and it can be used to synthesize immune stimulating antibody conjugate (ISAC) molecules. TLR7/8 agonist 7 can be used for the research of immunity.
体外研究:
TLR7/8 agonist 7 (compound 10) (0-1 μΜ; 24 h) is a TLR7 agonist and shows selectivity to TLR7.TLR7/8 agonist 7 (compound 10) (0-1 μΜ; 120 h) shows no cytotoxicity to KB cells.TLR7/8 agonist 7 (compound 10) (0.01, 0.1, 1, 10, 100 and 1000 nM; 48 h) induces immune cells activation.TLR7/8 agonist 7 (compound 10) (0.1, 1, 10, 100 and 1000 nM; 24-48 h) induces cytokine release.