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编 号：F753788
分子式：C15H16N2Na4O18P4
分子量：728.14
分子式：C15H16N2Na4O18P4
分子量：728.14
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CAS No: 2567869-47-8
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生物活性：
MRS2768 tetrasodium salt is a moderately potent and selective P2Y2 receptor agonist. MRS2768 tetrasodium salt has a protective effect on cardiomyocytes from ischemic damage in vivo and in vitro.
体内研究：
MRS2768 (4.44 μg/kg i.v.) pretreatment reduces myocardial damage in mice. MRS2768 has a protective effect on cardiomyocytes from ischemic damage in vivo.Animal Model:Male wild-type mice (C57BL)
Dosage:4.44 μg/kg
Administration:Injected i.v.; 1 h before myocardial infarct (MI)
Result:Pretreatment reduced myocardial damage. The damage was significantly smaller in mice compare to the untreated mice (25.6±4.5% vs. 39.2±6.3%).
体外研究：
MRS2768 (0.01-10000 μM; 24 hours) significantly increases the proliferation of PANC-1 cells.
MRS2768 tetrasodium salt is a moderately potent and selective P2Y2 receptor agonist. MRS2768 tetrasodium salt has a protective effect on cardiomyocytes from ischemic damage in vivo and in vitro.
体内研究：
MRS2768 (4.44 μg/kg i.v.) pretreatment reduces myocardial damage in mice. MRS2768 has a protective effect on cardiomyocytes from ischemic damage in vivo.Animal Model:Male wild-type mice (C57BL)
Dosage:4.44 μg/kg
Administration:Injected i.v.; 1 h before myocardial infarct (MI)
Result:Pretreatment reduced myocardial damage. The damage was significantly smaller in mice compare to the untreated mice (25.6±4.5% vs. 39.2±6.3%).
体外研究：
MRS2768 (0.01-10000 μM; 24 hours) significantly increases the proliferation of PANC-1 cells.
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