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编 号：F753679
分子式：C34H55N3O4S
分子量：601.88
分子式：C34H55N3O4S
分子量：601.88
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CAS No: 2551067-10-6
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生物活性：
Apoptosis inducer 9 induces apoptosis with IC50 value of 4.21 μM. Apoptosis inducer 9 induces apoptosis through the mitochondrial pathway and enhance the expression of Cl-caspase-3, Cl-caspase-9 and Cl-PARP. Apoptosis inducer 9 can be used the potential to develop new anti-proliferative agents.
体外研究：
Apoptosis inducer 9 (Compound A1) (5-10 μM, 12 hours) induces apoptosis in HepG-2 cells in a concentration-dependent manner.Apoptosis inducer 9 (Compound A1) (0-20 μM, 24 hours) triggers Cl-caspase-3, Cl-caspase-9 and Cl-PARP protein expression in HepG-2, thereby inducing apoptosis.Apoptosis inducer 9 (Compound A1) (0-20 μM, 24 hours) induces apoptosis by triggering the mitochondrial apoptosis pathway.
Apoptosis inducer 9 induces apoptosis with IC50 value of 4.21 μM. Apoptosis inducer 9 induces apoptosis through the mitochondrial pathway and enhance the expression of Cl-caspase-3, Cl-caspase-9 and Cl-PARP. Apoptosis inducer 9 can be used the potential to develop new anti-proliferative agents.
体外研究：
Apoptosis inducer 9 (Compound A1) (5-10 μM, 12 hours) induces apoptosis in HepG-2 cells in a concentration-dependent manner.Apoptosis inducer 9 (Compound A1) (0-20 μM, 24 hours) triggers Cl-caspase-3, Cl-caspase-9 and Cl-PARP protein expression in HepG-2, thereby inducing apoptosis.Apoptosis inducer 9 (Compound A1) (0-20 μM, 24 hours) induces apoptosis by triggering the mitochondrial apoptosis pathway.
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