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编 号:F753667
分子式:C24H19N7O4S
分子量:501.52
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hA2A/hCA XII modulator 1 (compound 14), a triazolopirazine, is a potent hA2A?adenosine receptor (hA2AAR) antagonist with Kis of 6.4 nM, 4.819 μM, >30 μM for hA2AAR, hA1AR, hA3AR, respectively. hA2A/hCA XII modulator 1 is a potent human carbonic anhydrase XII (hCA XII) inhibitor with Kis of 6.2 nM, 46 nM, 466 nM, 8.351 μM for hCA XII, hCA II, hCA IX and hCA I, respectively. hA2A/hCA XII modulator 1 has?the?potential?for?cancer?research.
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