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编 号:F753649
分子式:C17H15N3O2
分子量:293.32
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生物活性:
ZC0101 is a potent, orally active IDO1 and TrxR dual inhibitor with IC50 values of 0.084 μM and 7.98 μM, respectively. ZC0101 effectively induces apoptosis and ROS accumulation in cancer cells.

体内研究:
ZC0101 (60 mg/kg; p.o.; once) effectively suppresses IDO1 activity in vivo.
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