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编 号:F753581
分子式:C26H36O8
分子量:476.56
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生物活性:
Kurzipene D (compound 4) is a potent anticancer agent. Kurzipene D induces the apoptosis and arrested the HepG2 cell cycle at S stage. Kurzipene D shows anti-tumor effects using in vivo zebrafish model. Kurzipene D has the property of inhibiting tumor proliferation and migration.

体外研究:
Kurzipene D (compound 4) shows strong cytotoxic activity against cancer cells K562, HepG2, A549, and HeLa, with IC50 values of 7.2 ± 0.4, 9.7 ± 0.3, 10.9 ± 0.6, and 12.4 ± 1.0, respectively.
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