产品
编 号：F753390
分子式：C28H21N3O3S
分子量：479.55
分子式：C28H21N3O3S
分子量：479.55
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CAS No: 2497504-72-8
产品详情
生物活性：
hCAIX-IN-10 (Compound 6i) is a selective carbonic anhydrase IX and XII inhibitor with Ki s of 61.5 and 586.8 nM for hCA IX and hCA XII, respectively. ?hCA IX and hCA XII are transmembrane isoforms which have been characterized as biomarkers for several types of tumors. The hCA XII assists in maintenance of acid-base homoeostasis in normal as well as tumor cells.
体外研究：
hCAIX-IN-10 (compound 6i) is a strong inhibitor of hCA IX rather than hCA XII in vitro.hCAIX-IN-10 (0.1 nM-0.1 mM; 6 h) inhibits carbonic anhydrases enzyme activity.
hCAIX-IN-10 (Compound 6i) is a selective carbonic anhydrase IX and XII inhibitor with Ki s of 61.5 and 586.8 nM for hCA IX and hCA XII, respectively. ?hCA IX and hCA XII are transmembrane isoforms which have been characterized as biomarkers for several types of tumors. The hCA XII assists in maintenance of acid-base homoeostasis in normal as well as tumor cells.
体外研究：
hCAIX-IN-10 (compound 6i) is a strong inhibitor of hCA IX rather than hCA XII in vitro.hCAIX-IN-10 (0.1 nM-0.1 mM; 6 h) inhibits carbonic anhydrases enzyme activity.
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