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编 号:F753331
分子式:C24H18N2O3S
分子量:414.48
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生物活性:
Tubulin polymerization-IN-25 (compound 17f) is a dual inhibitor of tubulin polymerization and farnesyl transferase (FTase) with IC50s of 1.11 μM and 0.39 μM, respectively. Tubulin polymerization-IN-25 displays cytotoxicity and excellent antitumor activity .

体外研究:
Tubulin polymerization-IN-25 (compound 17f) is a dual inhibitor (MTI-FTI hybrids) acting on tubulin polymerization and on FTase.Tubulin polymerization-IN-25 (10 μM, 48 h) inhibits cells growth and induces cell cytotoxicity on multiple cancer cell lines.
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