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编 号:F753329
分子式:C12H6ClN5O2S
分子量:319.73
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生物活性:
Apoptotic agent-1 (Compound 8a) is an apoptotic agent with high antiproliferative activity against cancer cells and low cytotoxic effect. Apoptotic agent-1 induces over-expression of Fas receptor and Cyto C genes.

体外研究:
Apoptotic agent-1 (Compound 8a) shows antiproliferative activity with IC50 values of 53.3, 12.9 and > 100 μM against HepG2, MCF-7 and WI-38 cells, respectively.
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