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编 号：F753319
分子式：C25H22N4O4
分子量：442.47
分子式：C25H22N4O4
分子量：442.47
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CAS No: 2490154-44-2
产品详情
生物活性：
Anti-MRSA agent 5 (B14) is a potent MRSAagent with MIC50 values of 0.38 μg/mL and has low hERG activity with an IC50 values of >40 μM. Anti-MRSA agent 5 (B14) also has low cytotoxicity to mammal cells and unlikely to acquire bacterial resistance.
体外研究：
Anti-MRSA agent 5 (B14) is highly selective toxic in bacterial cells. Anti-MRSA agent has marginal inhibitory activities with an IC50 values of exceeding 40 μM. Anti-MRSA agent 5 (B14) has strong antibacterial activity for all five clinical isolates of MRSA (NRS-1, NRS-70, NRS-100, NRS-108, NRS-271) with MIC values between Anti-MRSA agent 5 相关抗体:Cell Cytotoxicity AssayCell Line:A549, MDA-MB-231, PC-3, ABAE.
Concentration:0–400 μM
Incubation Time:48h
Result:Showed marginal inhibitory activities with anIC50 exceeding 40 μM and displayed highly selective toxicity toward bacterial cells.
Anti-MRSA agent 5 (B14) is a potent MRSAagent with MIC50 values of 0.38 μg/mL and has low hERG activity with an IC50 values of >40 μM. Anti-MRSA agent 5 (B14) also has low cytotoxicity to mammal cells and unlikely to acquire bacterial resistance.
体外研究：
Anti-MRSA agent 5 (B14) is highly selective toxic in bacterial cells. Anti-MRSA agent has marginal inhibitory activities with an IC50 values of exceeding 40 μM. Anti-MRSA agent 5 (B14) has strong antibacterial activity for all five clinical isolates of MRSA (NRS-1, NRS-70, NRS-100, NRS-108, NRS-271) with MIC values between Anti-MRSA agent 5 相关抗体:Cell Cytotoxicity AssayCell Line:A549, MDA-MB-231, PC-3, ABAE.
Concentration:0–400 μM
Incubation Time:48h
Result:Showed marginal inhibitory activities with anIC50 exceeding 40 μM and displayed highly selective toxicity toward bacterial cells.
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