产品
编 号：F753291
分子式：C21H32N8O2
分子量：428.53
分子式：C21H32N8O2
分子量：428.53
产品类型
规格
价格
是否有货
结构图
CAS No: 2488943-55-9
产品详情
生物活性：
CXCR4 modulator-2 (compound Z7R) is a highly potent CXCR4 modulator with an IC50 value of 1.25 nM. CXCR4 modulator-2 has acceptable stability (t1/2 = 77.1 min) in mouse serum and exhibits anti-inflammatory activity in mouse edema model.
体内研究：
CXCR4 modulator-2 (10 mg/kg; IP; single dosage) significantly reduces the edema weights (～50%) in the lesion and decreases the expression of CXCR4s.Animal Model:male nude mice (6 weeks, 20 g; subcutaneous injection of 50 μL of λ-carrageenan)
Dosage:10 mg/kg
Administration:IP; single dosage
Result:Significantly reduced the edema weights (～50%) in the lesion and decreased the expression of CXCR4s.
CXCR4 modulator-2 (compound Z7R) is a highly potent CXCR4 modulator with an IC50 value of 1.25 nM. CXCR4 modulator-2 has acceptable stability (t1/2 = 77.1 min) in mouse serum and exhibits anti-inflammatory activity in mouse edema model.
体内研究：
CXCR4 modulator-2 (10 mg/kg; IP; single dosage) significantly reduces the edema weights (～50%) in the lesion and decreases the expression of CXCR4s.Animal Model:male nude mice (6 weeks, 20 g; subcutaneous injection of 50 μL of λ-carrageenan)
Dosage:10 mg/kg
Administration:IP; single dosage
Result:Significantly reduced the edema weights (～50%) in the lesion and decreased the expression of CXCR4s.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备