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编 号:F753284
分子式:C18H27F2N5O2
分子量:383.44
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生物活性:
FGFR-IN-3 (compound 6) is an orally active, potent and BBB-penetrated FGFR (fibroblast growth factor receptor) modulator. FGFR-IN-3 shows neuroprotective activity. FGFR-IN-3 can be used for neurodegenerative diseases research.

体内研究:
FGFR-IN-3 (compound 6) is sufficiently lipophilic (logP = 2.2) to passively permeate across the blood-brain barrier, and further increase in molecular lipophilicity results in boosting MBI (mechanism-based inactivation) activity.
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