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编 号:F753253
分子式:C26H20ClN5O2
分子量:469.92
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生物活性:
PAK1-IN-1 is a potent and selective PAK1 inhibitor with an IC50 of 9.8 nM. PAK1-IN-1 inhibits the migration and invasion of PAK1-related tumour cells in a dose-dependent manner.

体外研究:
PAK1-IN-1 (compound 30l) (0-10 μM) shows selectivity with IC50s of 0.01, >10 μM for PAK1 and PAK4, respectively.
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