产品
编 号：F753143
分子式：C17H16ClN3O2S
分子量：361.85
分子式：C17H16ClN3O2S
分子量：361.85
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规格
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结构图
CAS No: 2481484-51-7
产品详情
生物活性：
COX-2/5-LOX-IN-3 (compound 5b) is a potent and dual COX-2/5-LOX inhibitor with IC50 values of 45.73, 5.45 and 4.33 μM for COX-1, COX-2, and 5-LOX, respectively. COX-2/5-LOX-IN-3 has the potential for the research of inflammation diseases.
体内研究：
COX-2/5-LOX-IN-3 (compound 5b) (p.o.; male Sprague Dawley rats) shows anti-inflammatory activities in vivo.Animal Model:Male Sprague Dawley rats
Dosage:2.622 X 10-5 mol/kg
Administration:Oral administration
Result:The percentage inhibition of edema (%I) reached 58.77% after 4h.
COX-2/5-LOX-IN-3 (compound 5b) is a potent and dual COX-2/5-LOX inhibitor with IC50 values of 45.73, 5.45 and 4.33 μM for COX-1, COX-2, and 5-LOX, respectively. COX-2/5-LOX-IN-3 has the potential for the research of inflammation diseases.
体内研究：
COX-2/5-LOX-IN-3 (compound 5b) (p.o.; male Sprague Dawley rats) shows anti-inflammatory activities in vivo.Animal Model:Male Sprague Dawley rats
Dosage:2.622 X 10-5 mol/kg
Administration:Oral administration
Result:The percentage inhibition of edema (%I) reached 58.77% after 4h.
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