产品
编 号：F753137
分子式：C12H12N4O5S2
分子量：356.38
分子式：C12H12N4O5S2
分子量：356.38
产品类型
规格
价格
是否有货
结构图
CAS No: 2480283-75-6
产品详情
生物活性：
hCAI/II-IN-2 (compound 2b) is a potent dual hCA I/II inhibitor with Ki values of 40.97, 15.15 and 61.88 nM for hCA I, hCA II and hCA Ⅸ. hCAI/II-IN-2 possesses anti-hypoxic activity against acute mountain sickness (AMS) and low cellular activity.
体内研究：
Animal Model:Male BLAB/c mice
Dosage:400 mg/kg
Administration:Oral administration; 14 days.
Result:Prolonged the survival time of mice by 21.7% compared with the blank control group.
体外研究：
hCAI/II-IN-2 (compound 2b) (5-200 μM, 48 hours; HEK293T cells) has no obvious toxicity at HEK293T cells.
hCAI/II-IN-2 (compound 2b) is a potent dual hCA I/II inhibitor with Ki values of 40.97, 15.15 and 61.88 nM for hCA I, hCA II and hCA Ⅸ. hCAI/II-IN-2 possesses anti-hypoxic activity against acute mountain sickness (AMS) and low cellular activity.
体内研究：
Animal Model:Male BLAB/c mice
Dosage:400 mg/kg
Administration:Oral administration; 14 days.
Result:Prolonged the survival time of mice by 21.7% compared with the blank control group.
体外研究：
hCAI/II-IN-2 (compound 2b) (5-200 μM, 48 hours; HEK293T cells) has no obvious toxicity at HEK293T cells.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备