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编 号:F753117
分子式:C23H20N4OS
分子量:400.5
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结构图
CAS No: 2477725-18-9
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生物活性:
B-Raf IN 9 (compound 8b) is a potent B-Raf inhibitor, with an IC50 of 24.79 nM. B-Raf IN 9 induces apoptosis and shows cell cycle arrest at G2/M phase. B-Raf IN 9 exhibits potent antitumor activity against human prostate cancer PC-3 cell line, with an IC50 of 7.83 μM.