产品
编 号:F753110
分子式:C24H24N6O2
分子量:428.49
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结构图
CAS No: 2476764-11-9
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生物活性:
MPO-IN-5 (compound 1) is a potent, irreversible MPO (myeloperoxidase) inhibitor. MPO-IN-5 inhibits MPO peroxidation and hERG binding, with IC50 values of 0.22 and 2.8 μM, respectively. MPO-IN-5 shows rapid kinetics of inhibition, with enzyme inactivation rate (kinact/Ki) of 23000 M?1s?1.